COMPARISON OF PATIENT SETUP ERRORS BY MEGAVOLTAGE IMAGING DAILY AND WEEKLY CBCT FOR IGRT IN PROSTATE CANCER

Nirmal Arasu, Jayesh Singh, Ankita Parikh, U. Suryanarayana

Abstract


Aim: To assess the setup errors by mega voltage imaging alone daily (EPID) and by cone beam computed tomography imaging weekly (CBCT).
And evaluate the advantage of CBCT over EPID. Twenty patients with primary prostatic adenocarcinoma treated Method: with denitive
radiotherapy by Image guided radiotherapy (IGRT) during June 2016 to June 2018. EPID was taken daily and CBCT weekly to assess setup errors.
Result: Analyzing all match results, mean values of shifts for EPID match results in lateral, longitudinal and vertical directions with SD (both in
cm) equaled: -0.025±0.277, 0.3±0.57 and -0.1±0.532, respectively. The same values achieved based on CBCT matching equaled: -0.01±0.237,
0.259±0.473 and -0.043±0.24, respectively. EPID and CBCT match results collected during the treatment process were analyzed to track the
possible dependence on the position verication technique suggestive of signicant change between EPID and CBCT match results was found only
in vertical direction. Conclusion: We can conclude that both verication techniques, based on MV imaging Electronic Portal Imaging Device and
Cone Beam CT, are imperative to maintain a proper patient's position during the irradiation process and consequently, improve reproducibility of
eld placement. Each technique has its merits and demerits.


Keywords


Prostatic Adenocarcinoma, IGRT, EPID, CBCT

Full Text:

PDF

References


Dasher B. Portal Design In Radiation Therapy. Second. USA: The R.L. Bryan Company;

223 p.

Schulze D, Liang J, Yan D, Zhang T. Comparison of various online IGRT strategies: The

benets of online treatment plan re-optimization. Radiother Oncol. 2009 Mar;90(3):

-76. doi: 10.1016/j.radonc.2008.08.012. Epub 2008 Oct 29. PMID: 18976828;

PMCID: PMC2713443.van Zijtveld M, Dirkx M, Breuers M, Kuipers R, Heijmen B.

Evaluation of the 'dose of the day' for IMRT prostate cancer patients derived from portal

dose measurements and cone-beam CT. Radiother Oncol. 2010 Aug 1;96(2):172–7.

Hurkmans CW, Remeijer P, Lebesque JV, Mijnheer BJ. Set-up verication using portal

imaging; review of current clinical practice. Radiother Oncol. 2001 Feb;58(2):105-20.

doi: 10.1016/s0167-8140(00)00260-7. PMID: 11166861.

Milecki P, Nawrocki S, Malicki J, Stryczyńska G. Evaluation of an electronic portal

imaging device (target view, ge) as a quality assurance tool. Rep Pract Oncol Radiother.

;6(4):169–72.

Piotrowski T, Martenka P, de PATOUL N, Jodda A, Coevoet M, Malicki J, et al. The new

two-component conformity index formula (TCCI) and dose-volume comparisons of the

pituitary gland and tonsil cancer IMRT plans using a linear accelerator and helical

Tomotherapy. Rep Pract Oncol Radiother. 2009;14(4):133–145.

Logadóttir Á, Korreman S, Petersen PM. Comparison of the accuracy and precision of

prostate localization with 2D–2D and 3D images. Radiother Oncol. 2011;

(2):175–180.

Boda-Heggemann J, Köhler F, Wertz H, Welzel G, Riesenacker N, Schäfer J, et al.

Fiducial-based quantication of prostate tilt using cone beam computer tomography

(CBCT). Radiother Oncol. 2007;85(2):247–250.

Sandhu A, Sethi R, Rice R, Wang J-Z, Marcus L, Salem C, et al. Prostate bed localization

with image-guided approach using on-board imaging: reporting acute toxicity and

implications for radiation therapy planning following prostatectomy. Radiother Oncol.

;88(1):20–25.

Haworth A, Kearvell R, Greer PB, Hooton B, Denham JW, Lamb D, et al. Assuring high

quality treatment delivery in clinical trials–results from the Trans-Tasman Radiation

Oncology Group (TROG) study 03.04 “RADAR” set-up accuracy study. Radiother

Oncol. 2009;90(3):299–306.

Van Haaren PMA, Bel A, Hofman P, van Vulpen M, Kotte ANTJ, van der Heide UA.

Inuence of daily setup measurements and corrections on the estimated delivered dose

during IMRT treatment of prostate cancer patients. Radiother Oncol. 2009 Mar

;90(3):291–8.

Verellen D, De Ridder M, Linthout N, Tournel K, Soete G, Storme G. Innovations in

image-guided radiotherapy. Nat Rev Cancer. 2007;7(12):949.


Refbacks

  • There are currently no refbacks.